This paper examines the geometries of basic straight microneedle arrays, slanted channel arrays with varying angles, and arrays with diverging and converging interior cross sections for the purpose of interstitial fluid extraction and transdermal drug delivery. Flow behaviour is analyzed under biometric pressure driven conditions including frictional losses, minor losses due to the array geometry, and losses due to electrokinetic effect in microchannels. This paper also presents design and fabrication details of preliminary work that will lead to a design for microneedle arrays.
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Fluid Flow Behaviour in Microneedle Arrays
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San, AN, Ben Mrad, R, & Sullivan, P. "Fluid Flow Behaviour in Microneedle Arrays." Proceedings of the ASME 3rd International Conference on Microchannels and Minichannels. ASME 3rd International Conference on Microchannels and Minichannels, Part B cont’d. Toronto, Ontario, Canada. June 13–15, 2005. pp. 511-515. ASME. https://doi.org/10.1115/ICMM2005-75162
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