Microfludic devices with integrated electrical detection will enable fast, low-cost or portable sensing and processing of biological and chemical samples. As an inherent property of microfabrication, micro-electrical impedance spectroscopy detectors can take advantage of AC electrokinetics for particle manipulation, leading to enhanced sensitivity. Preliminary experiments on particle detection were carried out using microelectrode pairs, and impedance spectra are compared with respect to opposite effects of dielectrophoresis and electrode polarization. The values of cell equivalent circuit are extracted for electrode optimization.
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Copyright © 2004
by ASME
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