In this study, both electro-dynamic balance (EDB) method and pendant droplet method were employed to study the evaporation and crystallization process of brine droplet. The EDB setup was used to levitate the charged micrometer sized droplets to study the evaporation process. The pendant droplet method could hang millimeter sized droplet to study the crystallization process. The evaporation of brine droplets with different mass concentrations was visualized by a high speed camera under different temperatures and relative humidity in the test chamber. The results showed that EDB method could get the accurate droplet evaporation results which obeyed the classic D2-law. It was found that the evaporation was increased with the decrease of relative humidity. Due to the attractive force provided by sodium and chloride ion on water molecules, evaporation rate of brine droplet was smaller than pure water, therefore the evaporation rate decreased with the increase of mass concentration by showing a linear relationship. In addition, a salt shell could be formed at the outside of droplet which still contained some amount of salt solution inside. Consequently, the water molecules need to overcome the pressure difference inside and outside the salt shell, and diffuse through the shell for further evaporation. For a higher relative humidity, a more round shell would be formed during the evaporation, and the growth of crystallization along the filament is weaker than that of smaller relative humidity. We hope this study can provide a different perspective to the heat transfer community about the evaporation of brine droplet.