Thermal analysis of a cylindrical tissue subject to a train of ultrashort pulse irradiations was made by developing a combined time-dependent radiation and conduction bio-heat transfer model. Ultrashort pulsed radiation transport in the cylindrical tissue is simulated using the transient discrete ordinate method. Treatment of focused beam is introduced. The model skin tissue is stratified as three layers with different optical, thermal and physiological properties. Comparisons between the collimated irradiation and focused beam are conducted. The effect of pulse train is investigated.

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