The present keynote speech overviews new frontiers of sensing techniques for thermophysical properties in micro and nano-scale processes which are being developed at Keio. Especially, new optical sensing techniques to measure wide variety of thermophysical properties such as thermal diffusivity, thermal conductivity, viscosity, mass diffusion coefficient and surface tension of novel fluids and solids in micro and nano-scale are presented with an emphasis on their industrial applications. All of these new optical techniques have high spatial and temporal resolutions which have never been attained by other conventional measurement tools.

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