In this paper, a CFD commercial code is used to evaluate the pressure drop through pipes in a stream of high pressure gas. Preliminarily, a grid sensitivity analysis is carried out by comparing CFD results with analytical results. Hybrid grids are used for this task. Each grid is characterized by a different number and thickness of layers in order to investigate the behavior of the grid with respect to the boundary layer. Then, the model based on the best performer grid is validated by using a literature test case, in which high pressure gas flow through a rough pipe is experimentally studied. Various equations of state (i.e. constant properties, ideal gas and Redlich-Kwong equation) and boundary conditions (e.g. pressure, mass flow, etc.) are taken into consideration. Finally, the model is used to extrapolate the behavior of different gases (i.e. natural gas, biogas and hydrogen-methane mixture) flowing at high pressure through pipes of different roughness.

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