We focus on the simulation of shock-driven material mixing powered by flow instabilities dependent on initial conditions (IC) at the material interfaces. Beyond complex multi-scale resolution issues of shocks and variable density turbulence, we must address the equally difficult problem of predicting flow transition promoted by energy deposited at the interfacial layers during the shock-interface interactions. Transition involves IC-dependent, large-scale coherent-structure dynamics capturable by a large eddy simulation (LES) strategy, but not by unsteady Reynolds-Averaged Navier-Stokes (URANS) approaches based on equilibrium developed turbulence assumptions and single-point-closure modeling. On the engineering end of computations, reduced-dimensionality (1D/2D) versions of such URANS tend to be preferred for faster turnaround in full-scale configurations. With suitable initialization around each transition, URANS can be used to simulate the subsequent near-equilibrium weakly turbulent flow. We demonstrate 3D state-of-the-art URANS performance around one such (reshock) transition — in the context of a sequential LES/URANS strategy.

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