In the present study, a problem of the hemodynamic fluid-structure interaction (FSI) in the carotid artery was analyzed using a numerical approach. To predict the blood flow and arterial deformation, a framework for the FSI analysis was developed by coupling computational fluid dynamics (CFD) and solid mechanics (CSM) approaches. Using this framework, the hemodynamics of the carotid artery was simulated with the patient-specific clinical data of the arterial geometry, pulsatile blood flow and blood rheology. It is found that the hemodynamic characteristics of the carotid artery are significantly affected by its geometric factors and flow conditions, and relatively low values of the wall shear stress were observed in the post-plaque dilated region of the carotid bifurcated area. Since these characteristics of the carotid artery are affected by the cerebral circulation system, the effects of the cardiac output and the distal vascular resistance on hemodynamics were also analyzed.

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