To explore the transient characteristic of a centrifugal pump with the specific speed of 90 during startup period, the internal three-dimensional unsteady flow was solved by using CFD. Wherein to overcome the difficulty in implement of boundary conditions in numerical simulation, a closed-loop pipe system that includes a centrifugal pump was built to accomplish self-coupling calculation. The results show that at the very beginning of startup, flow rate rises slowly and non-dimensional head coefficient is much higher than quasi-steady value, the quasi-assumption can not be competent for predicting transient effect well. Moreover, the insufficient of energy conversion makes the evolvement of transient flow field lags behind that of quasi-steady flow field, i.e., kinetic energy can’t convert pressure energy in time during acceleration flow period. Rotor-stator interaction makes flow rate present slight fluctuation characteristic under stable operating conditions.

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