Analysis of a Bubble Deformation Process in a Microcapsule for Developing Drug Delivery Systems Using Underwater Shock Waves

This paper describes development of microcapsule using underwater shock waves, especially (1) the trial of making smaller microcapsules including a bubble for shock wave drug delivery systems, and analysis of a bubble deformation process to have higher efficiency of disintegration by shock wave, and (2) the effects of gradient of cytokine concentration on neutrophile motion in liquid by observing the concentration transport process with adding cytokine for developing drug delivery systems.