The purpose of this study is to evaluate the flow pattern and the fluid shear stress acting on the retinal wall in a human eye vitreous chamber after Vitrectomy and gas tamponade including the effect of saccadic eye movements. The correlation between the maximum shear stress induced on the retinal wall and the gas fill fraction (GF) and saccade amplitudes was investigated. In modeling the geometry of vitreous chamber cavity, the indentation of the lens was taken into account. The two-phase flow at the recovery phase of the operation was modeled numerically. Unsteady three-dimensional forms of continuity and Navier-Stokes equations were solved. Volume-of-fluid method was used to solve the two-phase flow in the eye. Saccadic motion of the eye was modeled using the dynamic mesh technique. The numerical model was validated by comparing the results with the available analytical solutions and experimental data for a spherical model. Then, numerical simulation was performed based on the deformed sphere configuration, representing a more realistic model of vitreous chamber cavity. The simulation results were compared with the available numerical studies for the spherical geometry. Then the wall shear stress on the retina was computed and compared for various gas fractions. The potential effect of wall shear stress on the retinal detachment and the need for post-operation posturing in all studied cases were discussed.

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