Turbulent CFD simulations are performed for feline aorta flow to study the physiology of thrombus localization for hypertrophic cardiomyopathy (HCM) heart condition. Simulations are performed using pulsatile normal and HCM heart cardiac output velocity profiles consisting of a single peak and dual peak pattern, respectively. The predictions for the normal heart conditions are validated using experimental data. The mass outflow through the arteries compares within 1.15% of the expected values. The flow rate through the iliac artery during a cardiac cycle, and shear stress profile at infrarenal aorta cross-section also compares well with the experimental data. Most vortical structures are predicted during decreasing cardiac flow, and are located close to the renal and iliac arteries, consistent with CFD studies in the literature. The model is therefore judged to be reasonably accurate for HCM predictions. For the HCM heart conditions, outflow from all the abdominal arteries shows a trimodal pattern, with reverse flow during the secondary flow. Several vortices are predicted in the increasing secondary cardiac flow. The vortices are mostly located in the lower abdominal aorta between the renal artery and iliac trifurcation. Turbulence plays a significant role in this case, and affects flow in most of the abdominal aorta after the primary peak. Particle deposition occurs in the thoracic aorta, below the renal artery and above the trifurcation. Deposition in the lower abdominal aorta is identified due to presence of flow recirculation and low streamwise velocity.
Turbulent Simulations of Particle Deposition in Feline Aorta Flow for Hypertrophic Cardiomyopathy Heart Conditions
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Bhushan, S, Borse, M, Robinson, B, & Walters, K. "Turbulent Simulations of Particle Deposition in Feline Aorta Flow for Hypertrophic Cardiomyopathy Heart Conditions." Proceedings of the ASME/JSME/KSME 2015 Joint Fluids Engineering Conference. Volume 1: Symposia. Seoul, South Korea. July 26–31, 2015. V001T04A003. ASME. https://doi.org/10.1115/AJKFluids2015-4688
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