This paper proposes a novel multi-scale approach for three-dimensional non-invasive analysis of 3d bone models reconstructed from μCT/μMRI images. The feasibility of the proposed method is demonstrated on 2D models representing a simple 2D trabecular bone tissue structure. First, a fundamental domain decomposition method is applied to solve these models. Then, a numerical zoom technique is utilized for local solution enhancement. The proposed new multi-scale FE method has the potential to provide new insights into bone structure and behavior as a component of a computerized virtual biopsy system.

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