This paper proposes a control-oriented pressure wave model, utilizing outputs of a reaction-based two-zone engine combustion model developed earlier, to accurately predict the key knock characteristics. The model can be used for model-based knock prediction and control. An in-cylinder pressure wave model of oscillation magnitude decay is proposed and simplified to describe pressure oscillations due to knock combustion, and the boundary and initial conditions of the pressure wave model at knock onset are provided by the two-zone reaction-based combustion model. The proposed pressure wave model is calibrated using experimental data, and the chemical kinetic-based Arrhenius integral (ARI) and maximum amplitude of pressure oscillations (MAPO) are used as the evaluation criteria for predicting knock onset and intensity, and the knock frequency is studied with the fast Fourier transform (FFT). The calibrated model is validated for predicting knock onset timing, knock intensity and frequency. Simulation results are compared with the experimental ones to demonstrate the capability of predicting engine knock characteristics by the proposed model.