Experimental Stimulation of EDL Mouse Muscle With a Small Scale Two-Coil System

As a muscle activation treatment, magnetic stimulation can elicit current flow through appropriate amplitude and frequency to generate electrical currents, which will prompt activation in the muscle tissue. The design of an electromagnetic system serves as an alternative to direct electrical stimulation for treating muscles located deep inside the tissue, such as the laryngeal muscles, stimulated via output-based control systems. Through magnetic induction, we can implement electrical stimulation and target specific muscle activation. In light of this approach, our goal is to incorporate feedback control using an electromagnetic stimulation system. These studies, therefore, focus on assessing a linear Proportional-Integral (PI) controller and two nonlinear controllers, Model Reference Adaptive Controller (MRAC) and an Adaptive Augmented PI (ADP-PI) system, to identify the most appropriate controller providing effective stimulation of the muscle. Our work focuses on the feasibility of our system to carry out in vitro experiments on mouse skeletal muscle and the characterization of the two-coil system for future design of implantable systems in humans.