This paper seeks to determine the validity of two distinct tube-load models relating central aortic blood pressure to peripheral blood pressure in humans. Specifically a single-tube model (1-TL) and a serially connected two-tube (2-TL) model, both terminating in a Windkessel load, are considered as representations of the central aortic-peripheral arterial path. The validity and fidelity of the two models was assessed and compared quantitatively by fitting central aortic, radial and femoral blood pressures collected from 8 patients. Both models fitted the BP waveform pairs effectively, and were capable of estimating pulse travel time (PTT) accurately; also the model derived frequency responses were close to the empiric transfer function estimates derived from central and peripheral BP measurements. The 2-TL model was consistently better than 1-TL with statistical significance in terms of accuracy of the central aortic BP waveform, the average waveform RMSE were 2.52 mmHg versus 3.24 mmHg respectively (p<0.05).
- Dynamic Systems and Control Division
Modeling and System Identification of Arterial Hemodynamics in Humans
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Rashedi, M, Fazeli, N, Chappell, A, Wang, S, MacArthur, R, McMurtry, MS, Finegan, B, & Hahn, J. "Modeling and System Identification of Arterial Hemodynamics in Humans." Proceedings of the ASME 2013 Dynamic Systems and Control Conference. Volume 3: Nonlinear Estimation and Control; Optimization and Optimal Control; Piezoelectric Actuation and Nanoscale Control; Robotics and Manipulators; Sensing; System Identification (Estimation for Automotive Applications, Modeling, Therapeutic Control in Bio-Systems); Variable Structure/Sliding-Mode Control; Vehicles and Human Robotics; Vehicle Dynamics and Control; Vehicle Path Planning and Collision Avoidance; Vibrational and Mechanical Systems; Wind Energy Systems and Control. Palo Alto, California, USA. October 21–23, 2013. V003T43A003. ASME. https://doi.org/10.1115/DSCC2013-3848
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