Co-Regulation of Calcium and Delayed Rectifier Currents Maintains Neuronal Output in a Model of a Crustacean Cardiac Motor Neuron Available to Purchase

Homeostatic processes are widespread throughout all living systems, and the nervous system is no exception. Individual neurons as well as neuronal networks must maintain levels of excitability and connectivity to ensure that consistent functional output is achieved. Possible mechanisms for maintaining functional output using co-regulation of channel conductances is studied for a motor neuron, using a computational model. The results are both consistent with and extend the biological observations.