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Proceedings Papers

Cadaveric Evaluation of a Novel Convection-Enhanced Therapy Catheter System

Brianna Morales, John Rossmeisl, DVM, Chris Rylander, PhD
Proc. ASME. DMD2024, 2024 Design of Medical Devices Conference, V001T09A012, April 8–10, 2024
Publisher: American Society of Mechanical Engineers
Paper No: DMD2024-1089
https://doi.org/10.1115/DMD2024-1089
View Paper titled, Cadaveric Evaluation of a Novel Convection-Enhanced Therapy Catheter System
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Topics: Biological tissues, Catheters, Convection, Patient treatment, Microneedles, Imaging, Brain, Damage, Drug delivery systems, Silicone elastomers
Proceedings Papers

Burst, Leakage, and Constant Pressure Infusion Testing of a Convection Enhanced Drug Delivery System for Glioblastoma Treatment

Iman Salafian, Christopher G. Rylander
Proc. ASME. DMD2022, 2022 Design of Medical Devices Conference, V001T10A006, April 11–14, 2022
Publisher: American Society of Mechanical Engineers
Paper No: DMD2022-1060
https://doi.org/10.1115/DMD2022-1060
View Paper titled, Burst, Leakage, and Constant Pressure Infusion Testing of a Convection Enhanced Drug Delivery System for Glioblastoma Treatment
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Topics: Catheters, Convection, Drug delivery systems, Fibers, Flow (Dynamics), Food and Drug Administration, Frequency-domain analysis, Leakage, Microneedles, Pressure
Proceedings Papers

Additive Manufacturing of Medical Microdevices

Renc Saracaydin, Seth A. Hara
Proc. ASME. DMD2022, 2022 Design of Medical Devices Conference, V001T05A003, April 11–14, 2022
Publisher: American Society of Mechanical Engineers
Paper No: DMD2022-1042
https://doi.org/10.1115/DMD2022-1042
View Paper titled, Additive Manufacturing of Medical Microdevices
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Topics: Additive manufacturing, Biomedicine, Drug delivery systems, Microfluidics
Proceedings Papers

Design of a Soft, Self-Uncoiling Stent for Extended Retention of Drug Delivery in the Small Intestine

Sunandita Sarker, Ryan Jones, Gabriel Chow, Benjamin Terry
Proc. ASME. DMD2021, 2021 Design of Medical Devices Conference, V001T12A010, April 12–15, 2021
Publisher: American Society of Mechanical Engineers
Paper No: DMD2021-1063
https://doi.org/10.1115/DMD2021-1063
View Paper titled, Design of a Soft, Self-Uncoiling Stent for Extended Retention of Drug Delivery in the Small Intestine
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Topics: Biological tissues, Design, Drug delivery systems, Drugs, Microneedles, Stents
Proceedings Papers

Solid Fiber Inside Capillary and Modified Fusion-Spliced Fiber Optic Microneedle Devices

Jason N. Mehta, Christopher G. Rylander
Proc. ASME. DMD2020, 2020 Design of Medical Devices Conference, V001T10A010, April 6–9, 2020
Publisher: American Society of Mechanical Engineers
Paper No: DMD2020-9050
https://doi.org/10.1115/DMD2020-9050
View Paper titled, Solid Fiber Inside Capillary and Modified Fusion-Spliced Fiber Optic Microneedle Devices
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Topics: Fibers, Microneedles, Lasers, Manufacturing, Brain, Failure, Fluids, Catheters, Convection, Drug delivery systems
Proceedings Papers

Nasal Spray Device for Administration of Two-Part Drug Formulations

Davin Rautiola, Ronald A. Siegel
Proc. ASME. DMD2019, 2019 Design of Medical Devices Conference, V001T10A004, April 15–18, 2019
Publisher: American Society of Mechanical Engineers
Paper No: DMD2019-3216
https://doi.org/10.1115/DMD2019-3216
View Paper titled, Nasal Spray Device for Administration of Two-Part Drug Formulations
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Topics: Drugs, Sprays, Blood, Brain, Drug delivery systems, Engineering prototypes, Pressure, Propellants, Stability
Proceedings Papers

Insertion Force of Polydopamine-Coated Needle on Phantom Tissues

Kavi I. Patel, Sai T. R. Gidde, Haoqi Li, Tarun Podder, Fei Ren, Parsaoran Hutapea
Proc. ASME. DMD2019, 2019 Design of Medical Devices Conference, V001T06A005, April 15–18, 2019
Publisher: American Society of Mechanical Engineers
Paper No: DMD2019-3271
https://doi.org/10.1115/DMD2019-3271
View Paper titled, Insertion Force of Polydopamine-Coated Needle on Phantom Tissues
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Topics: Biological tissues, Needles, Phantoms, Biomedicine, Coating processes, Coatings, Damage, Friction, Ablation (Vaporization technology), Adhesion
Proceedings Papers

An In Silico Investigation of a Lobe-Specific Targeted Pulmonary Drug Delivery Method

Yu Feng, Xiaole Chen, Mingshi Yang
Proc. ASME. DMD2018, 2018 Design of Medical Devices Conference, V001T08A011, April 9–12, 2018
Publisher: American Society of Mechanical Engineers
Paper No: DMD2018-6928
https://doi.org/10.1115/DMD2018-6928
View Paper titled, An In Silico Investigation of a Lobe-Specific Targeted Pulmonary Drug Delivery Method
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Topics: Drug delivery systems, Drugs, Biomedicine, Particulate matter, Biological tissues, Design, Dynamics (Mechanics), Engineering prototypes, Flow (Dynamics), Fluids
Proceedings Papers

Design and Development of a Novel Drug Delivery Catheter for Atherosclerosis

Sunandita Sarker, Yiannis S. Chatzizisis, Srivatsan Kidambi, Benjamin S. Terry
Proc. ASME. DMD2018, 2018 Design of Medical Devices Conference, V001T01A006, April 9–12, 2018
Publisher: American Society of Mechanical Engineers
Paper No: DMD2018-6869
https://doi.org/10.1115/DMD2018-6869
View Paper titled, Design and Development of a Novel Drug Delivery Catheter for Atherosclerosis
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Topics: Atherosclerosis, Catheters, Design, Drug delivery systems, Diseases, Nanoparticles, Risk, Cardiovascular system, Drugs, Biological tissues
Proceedings Papers

Programmable Ultrasound Phased Array Therapy System

Yiying I. Zhu, Timothy L. Hall, Oliver D. Kripfgans
Proc. ASME. DMD2017, 2017 Design of Medical Devices Conference, V001T08A008, April 10–13, 2017
Publisher: American Society of Mechanical Engineers
Paper No: DMD2017-3370
https://doi.org/10.1115/DMD2017-3370
View Paper titled, Programmable Ultrasound Phased Array Therapy System
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Topics: Patient treatment, Ultrasound, Cycles, Design, Ablation (Vaporization technology), Acoustics, Biological tissues, Transients (Dynamics), Bone, Circuits
Proceedings Papers

Insertion Mechanics of 3D Printed Honeybee-Inspired Needle Prototypes for Percutaneous Procedure

Mohammad Sahlabadi, David Gardell, Jonasan Younan Attia, Seyedvahid Khodaei, Parsaoran Hutapea
Proc. ASME. DMD2017, 2017 Design of Medical Devices Conference, V001T08A020, April 10–13, 2017
Publisher: American Society of Mechanical Engineers
Paper No: DMD2017-3457
https://doi.org/10.1115/DMD2017-3457
View Paper titled, Insertion Mechanics of 3D Printed Honeybee-Inspired Needle Prototypes for Percutaneous Procedure
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Topics: Additive manufacturing, Engineering prototypes, Needles, Surgery, Biological tissues, Design, Trajectories (Physics), Biomedicine, Damage, Biomimetics
Proceedings Papers

Non-Linear Viscoplastic Material Modeling of the Degradation Response of PLA

Jorgen S. Bergstrom, David J. Quinn, Samual Chow, Sekar M. Govindarajan
Proc. ASME. FMD2013, ASME 2013 Conference on Frontiers in Medical Devices: Applications of Computer Modeling and Simulation, V001T10A028, September 11–13, 2013
Publisher: American Society of Mechanical Engineers
Paper No: FMD2013-16120
https://doi.org/10.1115/FMD2013-16120
View Paper titled, Non-Linear Viscoplastic Material Modeling of the Degradation Response of PLA
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Topics: Biomedicine, Constitutive equations, Drug delivery systems, Drugs, Engineering simulation, Flow (Dynamics), Mechanical behavior, Modeling, Simulation, Stents
Proceedings Papers

Combining Imaging Modalities in the Modelling of Multi Parameter Devices

Jens Vinge Nygaard
Proc. ASME. FMD2013, ASME 2013 Conference on Frontiers in Medical Devices: Applications of Computer Modeling and Simulation, V001T05A003, September 11–13, 2013
Publisher: American Society of Mechanical Engineers
Paper No: FMD2013-16124
https://doi.org/10.1115/FMD2013-16124
View Paper titled, Combining Imaging Modalities in the Modelling of Multi Parameter Devices
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Topics: Imaging, Modeling, Biocompatibility, Biological tissues, Computer simulation, Drug delivery systems, Flow (Dynamics), Magnetic resonance imaging, Medical devices, Numerical analysis
Proceedings Papers

Development of Minimal Invasive SMA Multi-Transducer Unit for Blood Analysis or Drug Delivery

Hidetake Yamamoto
Proc. ASME. BIOMED2010, ASME 2010 5th Frontiers in Biomedical Devices Conference and Exhibition, 71-77, September 20–21, 2010
Publisher: American Society of Mechanical Engineers
Paper No: BioMed2010-32008
https://doi.org/10.1115/BioMed2010-32008
View Paper titled, Development of Minimal Invasive SMA Multi-Transducer Unit for Blood Analysis or Drug Delivery
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Topics: Biomedicine, Blood, Drug delivery systems, Erythrocytes, Suction, Transducers
Proceedings Papers

A Novel Piezo-Driven Micro-Jet Injection System for Transdermal Drug Delivery

Kai Chen
Proc. ASME. BIOMED2009, ASME 2009 4th Frontiers in Biomedical Devices, 67-68, June 8–9, 2009
Publisher: American Society of Mechanical Engineers
Paper No: BioMed2009-83020
https://doi.org/10.1115/BioMed2009-83020
View Paper titled, A Novel Piezo-Driven Micro-Jet Injection System for Transdermal Drug Delivery
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Topics: Drug delivery systems, Displacement, Flow (Dynamics), Piezoelectric actuators, Screws
Proceedings Papers

Pulmonary Delivery of Isoproterenol Aerosol Generated With Silicon-Based MHz Ultrasonic Nozzles

S. C. Tsai, R. W. Mao, D. Mukai, S. K. Lin, J. Y. Yang, N. Wang, A. F. Wilson, M. Brenner, S. C. George, P. Wang, C. S. Tsai
Proc. ASME. BIOMED2009, ASME 2009 4th Frontiers in Biomedical Devices, 87-88, June 8–9, 2009
Publisher: American Society of Mechanical Engineers
Paper No: BioMed2009-83035
https://doi.org/10.1115/BioMed2009-83035
View Paper titled, Pulmonary Delivery of Isoproterenol Aerosol Generated With Silicon-Based MHz Ultrasonic Nozzles
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Topics: Aerosols, Nozzles, Silicon, Drops, Design, Drug delivery systems, Drugs, Electric propulsion, Ethanol, Microelectromechanical systems
Proceedings Papers

An Optical Fiber Biosensor for Monitoring Drug Delivery

Anisur Rahman, Reginald Eze, Sunil Kumar
Proc. ASME. BIOMED2007, ASME 2007 2nd Frontiers in Biomedical Devices, 155-156, June 7–8, 2007
Publisher: American Society of Mechanical Engineers
Paper No: BioMed2007-38103
https://doi.org/10.1115/BioMed2007-38103
View Paper titled, An Optical Fiber Biosensor for Monitoring Drug Delivery
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Topics: Biosensors, Drug delivery systems, Optical fiber, Manufacturing, Biomedicine, Computer simulation, Interferometers, Microelectromechanical systems, Microfluidics, Micromachining
Proceedings Papers

Prototype of Microcapsule for Shock Wave Drug Delivery Systems and Its Design

Masaaki Tamagawa
Proc. ASME. BIOMED2007, ASME 2007 2nd Frontiers in Biomedical Devices, 51-52, June 7–8, 2007
Publisher: American Society of Mechanical Engineers
Paper No: BioMed2007-38088
https://doi.org/10.1115/BioMed2007-38088
View Paper titled, Prototype of Microcapsule for Shock Wave Drug Delivery Systems and Its Design
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Topics: Design, Drug delivery systems, Engineering prototypes, Shock waves, Bubbles, Mechanical properties
Proceedings Papers

Fundamental Investigations of Driving Force of Microcapsule for Drug Delivery Systems Using the Principle of Neutrophile’s Chemotaxis

Masaaki Tamagawa
Proc. ASME. BIOMED2007, ASME 2007 2nd Frontiers in Biomedical Devices, 145-146, June 7–8, 2007
Publisher: American Society of Mechanical Engineers
Paper No: BioMed2007-38091
https://doi.org/10.1115/BioMed2007-38091
View Paper titled, Fundamental Investigations of Driving Force of Microcapsule for Drug Delivery Systems Using the Principle of Neutrophile’s Chemotaxis
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Topics: Drug delivery systems
Proceedings Papers

Electric Field Directed Fabrication of Biosensor Devices From Biomolecule Derivatized Nanoparticles

Michael J. Heller, Dieter Dehlinger, Sadik Esener, Benjamin Sullivan
Proc. ASME. BIOMED2007, ASME 2007 2nd Frontiers in Biomedical Devices, 53-54, June 7–8, 2007
Publisher: American Society of Mechanical Engineers
Paper No: BioMed2007-38093
https://doi.org/10.1115/BioMed2007-38093
View Paper titled, Electric Field Directed Fabrication of Biosensor Devices From Biomolecule Derivatized Nanoparticles
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Topics: Biosensors, Electric fields, Manufacturing, Nanoparticles, DNA, Glucose, Sensors, Chemistry, Complementary metal oxide semiconductors, Drug delivery systems