Congenital Tracheal Stenosis (CTS) is a rare birth defect requiring surgical interventions when it affects more than 30% of the trachea. Slide tracheoplasty, the current standard of care, is associated with reinterventions including the need for intraluminal stenting leading to increased airway infections. We propose a novel Bio-Synthetic Graft for long segment tracheal reconstructions in CTS patients. Preliminary bench performance testing, using lamb tracheas, shows that the Bio-Synthetic Graft reconstructed tracheas have comparable radial, axial and bending stiffness in hyperextension to healthy tracheas and resist collapse when subjected to bending in flexion. These results suggest that Bio-Synthetic Graft could be a promising alternative to existing solutions for long segment CTS.
Skip Nav Destination
2019 Design of Medical Devices Conference
April 15–18, 2019
Minneapolis, Minnesota, USA
ISBN:
978-0-7918-4103-7
PROCEEDINGS PAPER
Novel Bio-Synthetic Graft for Tracheal Reconstruction in Pediatric Patients With Congenital Tracheal Stenosis: In Vitro Studies of Axial, and Bending Biomechanics
Teja Karkhanis,
Teja Karkhanis
Texas A&M University, College Station, TX
Search for other works by this author on:
Farhan Zafar,
Farhan Zafar
University of Cincinnati, Cincinnati, OH
Search for other works by this author on:
Brian Juarez,
Brian Juarez
Texas A&M University, College Station, TX
Search for other works by this author on:
David Luis-Simon Morales,
David Luis-Simon Morales
University of Cincinnati, Cincinnati, OH
Search for other works by this author on:
Balakrishna Haridas
Balakrishna Haridas
Texas A&M University, College Station, TX
Search for other works by this author on:
Teja Karkhanis
Texas A&M University, College Station, TX
Farhan Zafar
University of Cincinnati, Cincinnati, OH
Brian Juarez
Texas A&M University, College Station, TX
David Luis-Simon Morales
University of Cincinnati, Cincinnati, OH
Balakrishna Haridas
Texas A&M University, College Station, TX
Paper No:
DMD2019-3226, V001T10A006; 5 pages
Published Online:
July 19, 2019
Citation
Karkhanis, T, Zafar, F, Juarez, B, Morales, DL, & Haridas, B. "Novel Bio-Synthetic Graft for Tracheal Reconstruction in Pediatric Patients With Congenital Tracheal Stenosis: In Vitro Studies of Axial, and Bending Biomechanics." Proceedings of the 2019 Design of Medical Devices Conference. 2019 Design of Medical Devices Conference. Minneapolis, Minnesota, USA. April 15–18, 2019. V001T10A006. ASME. https://doi.org/10.1115/DMD2019-3226
Download citation file:
409
Views
Related Proceedings Papers
Related Articles
Tracheal Cartilage Ring Biomechanical Properties for Pediatric Exostent Design
J. Med. Devices (June,2016)
Simulations of Congenital Septal Defect Closure and Reactivity Testing in Patient-Specific Models of the Pediatric Pulmonary Vasculature: A 3D Numerical Study With Fluid-Structure Interaction
J Biomech Eng (August,2006)
A Design Framework of Unloaded Leaflet Shape for the Ovine Pulmonary Valve Single Leaflet Replacement Surgery
J. Med. Devices (June,2011)
Related Chapters
Introduction
Mechanical Blood Trauma in Circulatory-Assist Devices
Performance Testing of Combined Cycle Power Plant
Handbook for Cogeneration and Combined Cycle Power Plants, Second Edition
Performance Analysis of Moments in Invariant Object Classification
Intelligent Engineering Systems through Artificial Neural Networks