Examination of Fluid-Structure Interaction in Stent Grafts and its Hemodynamic Implications

Every year in the United States, 4,500 deaths occur from abdominal aortic aneurysm (AAA) rupture. Aneurysms develop when the arterial wall weakens. Many risk factors can contribute to aneurysm formation, including age, sex, ethnicity, smoking and hypertension [1]. AAAs are the most common form of aneurysm because the aorta experiences the highest wall shear stress (WSS) of any vessels in the human body. These aneurysms are 5–6% prevalent in men and 1–2% in women, both over 65 years of age [2]. In the aorta, high WSS causes plaque formation, but in peripheral arteries where the flow rate is lower, atherosclerosis can also trigger aneurysm formation.