Recently, high intensity focused ultrasound (HIFU) has been used for non-invasive surgery of prostate, uterus, and brain. However, a HIFU therapy is suffered from relatively long surgical time mainly due to small focal area per each sonication. In order to solve this problem, a HIFU therapy using multi-frequency was suggested by several researchers, and they demonstrated that this technique can increase the area of the coagulated lesion due to enhanced cavitation effect compared to single-frequency HIFU [1–3]. To generate multi-frequency especially dual-frequency, dual-element and dual-layer HIFU transducers have been developed and provided an expanded lesion size [1–3]. In this study, we present an alternative technique of making dual-frequency HIFU transducer using inversion layer technique. Generally, a single layer piezoelectric element can excite the strong fundamental resonance (f0) and the weak odd-order harmonic resonance (3f0) . In the inversion layer technique, on the other hand, a piezoelectric component consisting of two piezo-ceramic plates bonded together with opposite poling directions and different thicknesses can produce the relatively strong even-order harmonic (2f0) in addition to the fundamental resonance . Additionally, only a pair of electrode at the outside of the each piezo-ceramic plate is required to stimulate dual-frequency ultrasound while two pairs of electrodes are typically required for conventional dual-element and dual-layer transducers [2,3]. A specially designed prototype HIFU transducer was built, and we verified that the dual-frequency ultrasound was successfully generated through electrical impedance and pulse-echo response measurements.
High Intensity Focused Ultrasound Transducer Using Inversion Layer Technique for Ultrasound Therapy
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Park, CY, Kwon, DS, Sung, JH, & Jeong, JS. "High Intensity Focused Ultrasound Transducer Using Inversion Layer Technique for Ultrasound Therapy." Proceedings of the 2017 Design of Medical Devices Conference. 2017 Design of Medical Devices Conference. Minneapolis, Minnesota, USA. April 10–13, 2017. V001T11A008. ASME. https://doi.org/10.1115/DMD2017-3369
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