The bioabsorbable thermoplastic Poly(lactic acid), PLA, is extensively used in many medical applications including surgical sutures, drug delivery systems, internal fixation devices, tissue engineering scaffolds, and drug eluting stents. Frequently, a PLA component is required to withstand mechanical loading for a desired amount of time and then degrade via hydrolysis. In its raw, undegraded form, PLA exhibits a non-linear, viscoplastic mechanical response. Through the degradation process, the modulus, yield stress and flow behavior of PLA changes. Accurate simulations of bioabsorbable implants require a constitutive model that accounts for the viscoplastic nature of the material and its evolution over time. In this work we present the development of a new material model framework for predicting the time-dependent viscoplastic response of PLA. The proposed material model also captures the change in mechanical behavior over time due to hydrolysis. The details of the proposed model are presented, and the model predictions are compared to preliminary experimental data.
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ASME 2013 Conference on Frontiers in Medical Devices: Applications of Computer Modeling and Simulation
September 11–13, 2013
Washington, DC, USA
Conference Sponsors:
- Bioengineering Division
ISBN:
978-0-7918-5600-0
PROCEEDINGS PAPER
Non-Linear Viscoplastic Material Modeling of the Degradation Response of PLA Available to Purchase
Jorgen S. Bergstrom,
Jorgen S. Bergstrom
Veryst Engineering, Needham, MA
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David J. Quinn,
David J. Quinn
Veryst Engineering, Needham, MA
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Sekar M. Govindarajan
Sekar M. Govindarajan
Veryst Engineering, Needham, MA
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Jorgen S. Bergstrom
Veryst Engineering, Needham, MA
David J. Quinn
Veryst Engineering, Needham, MA
Samual Chow
Veryst Engineering, Needham, MA
Sekar M. Govindarajan
Veryst Engineering, Needham, MA
Paper No:
FMD2013-16120, V001T10A028; 3 pages
Published Online:
February 19, 2014
Citation
Bergstrom, JS, Quinn, DJ, Chow, S, & Govindarajan, SM. "Non-Linear Viscoplastic Material Modeling of the Degradation Response of PLA." Proceedings of the ASME 2013 Conference on Frontiers in Medical Devices: Applications of Computer Modeling and Simulation. ASME 2013 Conference on Frontiers in Medical Devices: Applications of Computer Modeling and Simulation. Washington, DC, USA. September 11–13, 2013. V001T10A028. ASME. https://doi.org/10.1115/FMD2013-16120
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