Numerical models of the heart’s mitral valve are being used to study valve biomechanics, facilitate predictive surgical planning, and are used in the design and development of repair devices. These models have evolved from simple two-dimensional approximations to complex three-dimensional fully coupled fluid structure interaction models. However, to date these models lack direct one-to-one experimental validation. Moreover, as computational solvers vary considerably based on researcher implementation, experimental benchmark data are critically important to ensure model accuracy. To this end, a multi-modality in-vitro pulsatile left heart simulator was used to establish a database of geometric and hemodynamic boundary conditions coupled with resultant valvular and fluid mechanics.
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ASME 2013 Conference on Frontiers in Medical Devices: Applications of Computer Modeling and Simulation
September 11–13, 2013
Washington, DC, USA
Conference Sponsors:
- Bioengineering Division
ISBN:
978-0-7918-5600-0
PROCEEDINGS PAPER
Developing an Experimental Database for Mitral Valve Computational Modeling, Surgical Repair, and Device Evaluation
Jean-Pierre M. Rabbah,
Jean-Pierre M. Rabbah
Georgia Institute of Technology, Atlanta, GA
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Neelakantan Saikrishnan,
Neelakantan Saikrishnan
Georgia Institute of Technology, Atlanta, GA
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Andrew W. Siefert,
Andrew W. Siefert
Georgia Institute of Technology, Atlanta, GA
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Ajit P. Yoganathan
Ajit P. Yoganathan
Georgia Institute of Technology, Atlanta, GA
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Jean-Pierre M. Rabbah
Georgia Institute of Technology, Atlanta, GA
Neelakantan Saikrishnan
Georgia Institute of Technology, Atlanta, GA
Andrew W. Siefert
Georgia Institute of Technology, Atlanta, GA
Ajit P. Yoganathan
Georgia Institute of Technology, Atlanta, GA
Paper No:
FMD2013-16016, V001T10A002; 2 pages
Published Online:
February 19, 2014
Citation
Rabbah, JM, Saikrishnan, N, Siefert, AW, & Yoganathan, AP. "Developing an Experimental Database for Mitral Valve Computational Modeling, Surgical Repair, and Device Evaluation." Proceedings of the ASME 2013 Conference on Frontiers in Medical Devices: Applications of Computer Modeling and Simulation. ASME 2013 Conference on Frontiers in Medical Devices: Applications of Computer Modeling and Simulation. Washington, DC, USA. September 11–13, 2013. V001T10A002. ASME. https://doi.org/10.1115/FMD2013-16016
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