Heart valve prosthetics replace damaged, malfunctioning valves to improve a patient’s quality of life. Current mechanical valves are durable but suffer from thrombogenicity and flow separation, and can cause blood damage leading to coagulation. While bioprosthetic valves have better haemodynamic function than mechanical valves, the valves suffer from tears due to inflammation and collagen degradation. The absence of living tissue leaves them unable to repair themselves and their antigenicity must be masked. Complications due to thrombosis occur between 1.5% and 3% per year for current mechanical and bioprosthetic valves [1]. Polymeric valves have the potential to exhibit improved haemodynamic performance over mechanical valves without the complications associated with bioprosthetic valves; current issues associated with polymeric valves include calcification, hydrolysis, and durability [2].
Skip Nav Destination
ASME 2011 6th Frontiers in Biomedical Devices Conference
September 26–27, 2011
Irvine, California, USA
Conference Sponsors:
- Bioengineering Division
PROCEEDINGS PAPER
Blood Cell Adhesion on a Polymeric Heart Valve Leaflet Processed Using Magnetic Abrasive Finishing Available to Purchase
Taylor Boggs,
Taylor Boggs
University of Florida, Gainesville, FL
Search for other works by this author on:
Hitomi Yamaguchi,
Hitomi Yamaguchi
University of Florida, Gainesville, FL
Search for other works by this author on:
Roger Tran-Son-Tay,
Roger Tran-Son-Tay
University of Florida, Gainesville, FL
Search for other works by this author on:
Curt DeGroff,
Curt DeGroff
University of Florida, Gainesville, FL
Search for other works by this author on:
Faris Al-Mousily
Faris Al-Mousily
University of Florida, Gainesville, FL
Search for other works by this author on:
Taylor Boggs
University of Florida, Gainesville, FL
Hitomi Yamaguchi
University of Florida, Gainesville, FL
Roger Tran-Son-Tay
University of Florida, Gainesville, FL
Curt DeGroff
University of Florida, Gainesville, FL
Faris Al-Mousily
University of Florida, Gainesville, FL
Paper No:
BioMed2011-66011, pp. 15-16; 2 pages
Published Online:
July 18, 2013
Citation
Boggs, T, Yamaguchi, H, Tran-Son-Tay, R, DeGroff, C, & Al-Mousily, F. "Blood Cell Adhesion on a Polymeric Heart Valve Leaflet Processed Using Magnetic Abrasive Finishing." Proceedings of the ASME 2011 6th Frontiers in Biomedical Devices Conference. ASME 2011 6th Frontiers in Biomedical Devices Conference and Exhibition. Irvine, California, USA. September 26–27, 2011. pp. 15-16. ASME. https://doi.org/10.1115/BioMed2011-66011
Download citation file:
14
Views
Related Proceedings Papers
Related Articles
Numerical Study of Shear-Induced Thrombus Formation Over Aterial Stent Struts
J. Med. Devices (June,2009)
Design of a Pulsatile Flow Facility to Evaluate Thrombogenic Potential of Implantable Cardiac Devices
J Biomech Eng (April,2015)
Bioactive Magnetoelastic Materials as Coatings for Implantable Biomaterials
J. Med. Devices (June,2009)
Related Chapters
Introduction
Mechanical Blood Trauma in Circulatory-Assist Devices
Surface Analysis and Tools
Tribology of Mechanical Systems: A Guide to Present and Future Technologies
Vascular Prostheses: Innovative Properties
Vascular Graft Update: Safety and Performance