The aim of the present study was to evaluate the performance of Ventilan® coupled to the Volumatic® spacer. An experimental study was conducted using the four stage Multistage Liquid Impinger (MSLI). This enabled the observation that half of the pharmacological dose is retained within the body of the spacer. Therefore, the air flow inside the spacer was studied, along the respiratory cycle, using Fluent™. Several recirculation regions were observed inside the spacer that may influence the aerosol flow and also the deposition of the drug.
- Nanotechnology Institute
Experimental Study and CFD Analysis of the Volumatic® Spacer
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Abreu, S, Silva, L, Teixeira, SFCF, Antunes, H, Marques, H, & Ramalhete, N. "Experimental Study and CFD Analysis of the Volumatic® Spacer." Proceedings of the ASME 2008 3rd Frontiers in Biomedical Devices Conference. ASME 2008 3rd Frontiers in Biomedical Devices Conference. Irvine, California, USA. June 18–20, 2008. pp. 97-103. ASME. https://doi.org/10.1115/BioMed2008-38068
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