Diffuse optical tomography (DOT) is a recently emerging technique that uses arrays of sources and detectors to obtain spatially dependent optical parameters of tissue. DOT techniques have been applied for a wide range of applications, especially for breast and head as well as animal imaging. We have developed an integrated dynamic MR/DOT imaging system. This combined system can acquire MR and optical data simultaneously with a high temporal resolution. Hence, the enhancement kinetics of multiple MR and optical contrast agents can be monitored independently.

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