Biosensors are analytical devices to detect biological reactions. Fluorescence labeling is the most widely used method. Labeling free methods are desired in some cases because it can save the time and effort of the labeling step and provide real-time observation for the reactions.
A Label-Free Integrated Optics Biosensor by Diffraction Grating Coupler
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Lai, Z, Wang, Y, Sims, CE, Allbritton, N, Bachman, M, & Li, G. "A Label-Free Integrated Optics Biosensor by Diffraction Grating Coupler." Proceedings of the ASME 2007 2nd Frontiers in Biomedical Devices Conference. ASME 2007 2nd Frontiers in Biomedical Devices. Irvine, California, USA. June 7–8, 2007. pp. 67-68. ASME. https://doi.org/10.1115/BioMed2007-38076
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