Brain imaging requires high levels of precision and accuracy, especially for diagnostic or surgical applications. Histological sections represent the “gold standard” in high-resolution imaging. For high-fidelity volume renderings of stacks of histological sections image registration using linear and non-linear transformations is required. Non-invasive scanning techniques, such as MRI, CT, PET, etc., produce inherently lower resolution, but better aligned imagery. By combining invasive and non-invasive scanning techniques, the advantages of various modalities can be combined into a hybrid system which enables co-location of instantiated patient scans and high-resolution reference scans.
High-Fidelity Medical Visualization
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Meyer, J. "High-Fidelity Medical Visualization." Proceedings of the ASME 2007 2nd Frontiers in Biomedical Devices Conference. ASME 2007 2nd Frontiers in Biomedical Devices. Irvine, California, USA. June 7–8, 2007. pp. 5-6. ASME. https://doi.org/10.1115/BioMed2007-38102
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